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Christin Naumann, Dipl.-Biochem., PhD student

Christin comes from Frankfurt/Oder, Germany, studied biochemistry at the Martin Luther University at Halle (Saale), and did her Diplom in Bettina Hause's lab at the IPB on the trimerization of Arabidopsis ALLENE OXIDE CYCLASE 2, a key enzyme in jasmonate biosynthesis. Since Spetember 2011, Christin is working on substrate ID in protein quality control mutants.

Maria Klecker, M.Sc. (biochemistry/molecular biol.), PhD student   

Maria is from Höxter, Germany and decided to start a bachelor in biology at the University of Bayreuth where she studied Zn-hypersensitive Arabidopsis mutants with Stephan Clemens at the Department of Plant Physiology. She then continued to work in the master program in biochemistry and molecular biology. In her thesis and later as a research assistant, she investigated the role of galactolipids within the hypoxia response of Arabidopsis in Angelika Mustroph’s lab for plant genetics. Since December 2012, Maria is focussing on promotor activities and binding specificities of N-end rule components.

Frederik Faden, Dipl.-Biol., PhD student

Frederik was born in Siegburg, Germany, studied biology at the Rheinische Friedrich-Wilhelms Universität in Bonn, and worked with Dorothea Bartels at the IMBIO for his Diplom on Arabidopsis ALDEHYDE DEHYDROGENASE 3H1, which is very important in response to desiccation and salt stress. Since August 2011, Frederik is establishing a screening system for components of the protein degradation machinery.

Anne Kind, B.Sc. (biochemistry)

Anne was born in Dresden, Germany. After one year working as an au pair in London, 2010 she started to study biochemistry at the Martin Luther University Halle-Wittenberg. 2012 she got the ability to collect methodical and ethical experiences at the VetMed Uni Vienna (veterinary medical university) in Thomas Rülicke‘s lab. Now, under the supervision of Christin Naumann, she will purify and study two proteins of the N-end rule pathway, which play a major role in protein degradation.

Dieter Lange, B.Sc. (biochemistry), Master student

Dieter is from Dresden, Germany, and studies biochemistry at the Martin Luther University Halle-Wittenberg since 2008. He did his bachelor’s project about microbial communities in waste water in Ute Lechner’s group. There, he was involved in isolation and characterization of 16S rRNA and nitrate reductase genes from different species. Then, Dieter worked for six months in Marita Cohn’s group at Lunds Universitet, Sweden, on telomer binding proteins from Saccharomyces castellii. Now, he’s involved in conditional protein activity studies.

Carolin Mai, B.Sc. (biochemistry), Master student

Carolin comes from Hohenstein-Ernstthal, Germany, and studies biochemistry at the Martin Luther University Halle-Wittenberg since 2008. In 2011, she passed her bachelor thesis in the lab of Martin S. Staege at the university hospital and polyclinic of paediatrics (Universitätsklinik und Poliklinik für Kinder- und Jugendmedizin), on the subject of “analysis of expression and function of ADRM1 on Hodgkin lymphoma”. In our lab, she is analyzing the RPM1-INTERACTING PROTEIN 4 (RIN4) as a potential substrate of the N-End rule pathway.

 

Elisabeth Maluck, B.Sc. (biochemistry), Master student

Elisabeth is originally from Döbeln, a small saxonian city. Since October 2009, she studies biochemistry in Halle and got her bachelor’s degree in 2012 with work on phycobiliprotein–linker complexes of phycobilisomes from Cyanophora paradoxa in Ralf Bernd Klösgen’s lab. Having started in our lab, she’s compiling a huge synthetic DNA construct using Modular Cloning (MoClo), also known as Golden Gate Technology, in order to construct a translatable NERD inhibitor. Maria supervises her and we get a lot of support from Sylvestre Marillonnet at the IPB.

Stefan Mielke, B.Sc. (biochemistry), Master student

Stefan is from Forst (Lausitz) in Brandenburg, very close to the Polish border. He enrolled for biochemistry at the Martin Luther University Halle-Wittenberg in 2007 and worked throughout his Bachelor thesis in Bettina Hause’s lab at the IPB investigating the COI1-JAZ co-receptor of jasmonate perception(this hyperlink directs to a brand new and freely available review by Claus Wasternack and Bettina on jasmonate signaling etc.

 

Augustin C. Mot, Ph.D. (chemical biology), postdoc

Augustin was born in Nasaud, Romania and studied chemistry at Babes-Bolyai University, Cluj-Napoca where he graduated in 2008. His bachelor thesis was in the field of analytical chemistry, supervised by Costel Sarbu,and his master thesis (2009) focused on several bio-analytical techniques. He started working in the field of biochemistry in 2009 by joining the group of Radu Silaghi-Dumitrescu where he worked on haemoglobin and hemerythrin blood substitutes, copper enzymes (fungal laccase, plant ascorbate oxidase and human ceruloplasmin) and plant extracts projects, getting his PhD in 2012 at the same university with a thesisfocusing on a new Sclerotinia sclerotiorum laccase. He enriched his knowledge and practical skills during several research internships at University of Ioannina (Greece), University of Texas at San Antonio (USA) in Donald Kurtz’ lab, Leiden Institute of Chemistry (Netherlands) in Dirk Heering’s lab. Getting a Leibniz-DAAD Research Fellowship, he works in our group in a joint project with Bernhard Westermann on affinity/activity-based protein profiling (ABPP) of NERP E3 ligases. Therefore, he synthesizes new probes based on click-chemistry.

Pavel Reichman, M.Sc. (mol. biol./genetics), PhD student

Pavel is from Brno, Czech Republic and studied molecular biology and genetics at the Masaryk University, Brno. He did his bachelor’s thesis on histidine-containing phosphotransfer proteins (AHPs) at the Central-European Technology Institute (CEITEC), and received his master’s degree for work more specifically on AHP2. Then, he continued to work in the Mendel Centre for Genomics and Proteomics of Plant Systems under supervision of Jan Hejátkoon localization of proteins involved in hormonal signal transduction. Pavel is the founding member and president of Biomania, a Brno-based life science student organization. Since February 2013, Pavel is setting up cross-linking and expression approaches to identify binding partners of N-end rule components.

Michaela Reissland, undergrad research assistant 

Michaela comes from Gotha, Germany, and studies biochemistry at the Martin Luther University Halle-Wittenberg since 2009. She is representative of the biochemistry students council (Fachschaftsrat). In 2011, she worked in Luz Irina A. Calderón-Villalobos' lab at the IPB on auxin signaling. In our lab, she is trying to characterize conditional cell cycle kinase activity in vivo.

Florian Sperling, B.Sc. (biochemistry)

Florian comes from Frankfurt (Oder), Germany, and studies biochemistry at the Martin Luther University Halle-Wittenberg since 2010. In our lab, he is working on his bachelor thesis which should establish a screening system for fusion-peptides, which are substrates of the N-end rule pathway. Therefore he is working with the ek-Tag, a special sequence following the NERP and first described in the paper “The degradation signal in a short-lived protein” by A. Bachmair and A. Varshavsky. By following the attached  hyperlink you can get the original paper and further background information about the project Florian is working on.

 

Veit Enno, intern (biochemistry)

Veit joined the lab in July 2014 and is an expert in Western blotting and DNA extraction.

   

Nico Dissmeyer, PI   

Nico was born in Detmold, Germany, moved to Tübingen to study biochemistry and some philosophy. He moved on via Oregon State University, Corvallis, USA and the Freie Universität Berlin to study Biochemistry and Biophysics to get his PhD from the Universität zu Köln in 2009 for work on CYCLIN-DEPENDENT-KINASE A;1 and other cell cycle regulators at the Max Planck Institute for Plant Breeding Research at Vogelsang. For his PhD thesis, he received the Elisabeth Gateff Award 2010 of the German Genetics Society (Deutsche Gesellschaft für Genetik, GfG). After a postdoc at the Institut de Biologie Moléculaire des Plantes of the CNRS at Strasbourg, France, he came to the IPB in spring 2011. He is now heading the junior research group of the ScienceCampus Halle since October 2011. Since 2012, Nico is a "Young Leaders in Science" fellow of the Ernst Schering Foundation.

 

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